CCR7 Protein
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- Target See all CCR7 Proteins
- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
- Protein Type
- MNP Membrane Nanoparticle
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human CCR7 full length protein-MNP
- Top Product
- Discover our top product CCR7 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from PBS. Normally 5% – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
- Alternative Name
- CCR7 (CCR7 Products)
- Background
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BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1
The protein is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. - Molecular Weight
- The human full length CCR7 protein has a MW of 42.9 kDa
- UniProt
- P32248
- Pathways
- Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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