TLR5 Protein

Catalog No. ABIN7597223

This MNP Membrane Nanoparticle TLR5 protein is expressed in HEK-293 Cells.

Quick Overview for TLR5 Protein (ABIN7597223)

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Protein Type: MNP Membrane Nanoparticle

Origin: Human

Source: HEK-293 Cells

Product Details

Purpose: Human TLR5 full length protein-MNP

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from PBS. Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Alternative Name: TLR5

Background: MELIOS, SLE1, SLEB1, TIL3
Toll-like receptor (TLR) family plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.

Molecular Weight: The human full length TLR5 protein has a MW of 97.8 kDa

UniProt: O60602

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades