CD46 Protein (CD46) (AA 45-327) (Fc Tag)
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- Target See all CD46 Proteins
- CD46
- Protein Type
- Recombinant
- Protein Characteristics
- AA 45-327
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD46 protein is labelled with Fc Tag.
- Purpose
- Recombinant mouse CD46 protein with C-terminal human Fc tag
- Sequence
- Mouse CD46(Cys45-Asp327) hFc(Glu99-Ala330)
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CD46 Protein
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CD46 (CD46) (AA 35-343) protein (His tag)
CD46 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD46 (CD46) (AA 35-329) protein (His tag)CD46 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD46 (CD46) (AA 45-344) protein (His tag)CD46 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD46 (CD46) (AA 35-328) protein (His tag)CD46 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD46 (CD46) (AA 35-313) protein (His tag)CD46 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
CD46 (CD46) (AA 35-313) protein (His tag)CD46 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
CD46 (CD46) (AA 1-384) protein (GST tag)CD46 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
- Comment
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The protein was made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CD46
- Alternative Name
- CD46 (CD46 Products)
- Background
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Mcp
Predicted to enable cadherin binding activity. Predicted to contribute to endopeptidase activity. Predicted to be involved in several processes, including positive regulation of T cell activation, regulation of gene expression, and regulation of signal transduction. Predicted to be located in basolateral plasma membrane, cell surface, and inner acrosomal membrane. Predicted to be active in extracellular space and plasma membrane. Is expressed in testis. Used to study age related macular degeneration. Human ortholog(s) of this gene implicated in several diseases, including atypical hemolytic-uremic syndrome, hemolytic-uremic syndrome, meningococcal meningitis, multiple sclerosis, and pre-eclampsia. Orthologous to human CD46 (CD46 Molecule). [provided by Alliance of Genome Resources, Nov 2024] - Molecular Weight
- predicted molecular mass of 57.8 kDa after removal of the signal peptide. The apparent molecular mass of mCD46-hFc is 70-100 kDa due to glycosylation.
- UniProt
- O88174
- Pathways
- Regulation of Actin Filament Polymerization
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