DKK3 Protein (AA 22-350) (Fc Tag)
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- Target See all DKK3 products
- DKK3
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-350
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DKK3 protein is labelled with Fc Tag.
- Purpose
- Recombinant human DKK3 Protein with C-terminal human Fc tag
- Sequence
- DKK3(Ala22-Ile350) hFc(Glu99-Ala330)
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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DKK3 (AA 23-350) protein (His-Avi Tag)
Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
DKK3 (AA 23-350) protein (His-Avi Tag,Biotin)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
DKK3 (AA 1-350) protein (GST tag)Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
DKK3 (AA 22-350) protein (His tag)Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
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- Application Notes
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
- Comment
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The protein was made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- DKK3
- Abstract
- DKK3 Products
- Background
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RIG, CRRL, REIC
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] - Molecular Weight
- predicted molecular mass of 62.4 kDa after removal of the signal peptide. The apparent molecular mass of DKK3-hFc is 70-130 kDa due to glycosylation.
- UniProt
- Q9UBP4
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