Calcitonin Protein (Calca) (AA 85-116) (His-TRX)

Catalog No. ABIN7668282

Recombinant Calcitonin protein expressed in Escherichia coli (E. coli).

Quick Overview for Calcitonin Protein (Calca) (AA 85-116) (His-TRX) (ABIN7668282)

Target: Calcitonin (Calca)

Protein Type: Recombinant

Biological Activity: Inactive

Origin: Rat

Source: Escherichia coli (E. coli)

Purity: > 95 %

Product Details

Protein Characteristics: AA 85-116

Purification tag / Conjugate: This Calcitonin protein is labelled with His-TRX.

Purpose: Recombinant Rat Calcitonin/CT protein (TRX,His tag)

Sequence: Cys85-Pro116

Purification: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: < 10 EU/mg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: Calcitonin (Calca)

Alternative Name: Calcitonin,CT

Background: Calcitonin is a secreted protein which belongs to the calcitonin family. Calcitonin is cleaved into the following two chains: Calcitonin and Katacalcin. Katacalcin is a potent plasma calcium-lowering peptide. Calcitonin is a 32-amino acid linear polypeptide hormone. Calcitonin acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). Its importance in humans has not been as well established as its importance in other animals, as its function is usually not significant in the regulation of normal calcium homeostasis. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.,Calc,Calca,Calcitonin

Molecular Weight:

calculated_mw: 23.4 kDa

observed_mw: 22 kDa

UniProt: P01257