CD63 Protein (CD63) (His tag)

Catalog No. ABIN7668392

This Recombinant CD63 protein is expressed in HEK-293 Cells.

Quick Overview for CD63 Protein (CD63) (His tag) (ABIN7668392)

Target: CD63

Protein Type: Recombinant

Biological Activity: Inactive

Origin: Human

Source: HEK-293 Cells

Purity: > 95 %

Product Details

Purification tag / Conjugate: This CD63 protein is labelled with His tag.

Purpose: Recombinant Human CD63 protein (His tag)

Sequence: Ala 103-Val 203

Purification: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU/mg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: CD63

Alternative Name: CD63

Background: There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 63 (CD63) is a member of the CD family and the transmembrane 4 superfamily,also known as the tetraspanin family. CD63 is a cellular surface glycoprotein characterized by the presence of four bydrophobic domains. CD63 had functions in mediating signal transduction processes and then regulate variety of cellular processes such as cell proliferation, activation and motility. It has reported that CD63 protein associated with tumor progression and served as a blood platlet activation marker and the deficiency of this protein may be associated with Hermansky-Pudlak syndrome.,CD antigen CD63,CD63 antigen,Granulophysin,LAMP-3,Lysosomal-associated membrane protein 3,Melanoma-associated antigen ME491,OMA81H,Ocular melanoma-associated antigen,Tetraspanin-30,Tspan-30

Molecular Weight:

calculated_mw: 11 kDa

observed_mw: 20 kDa

UniProt: P08962