CXCL3 Protein (AA 32-100) (TRX tag)

Catalog No. ABIN7668514

This Recombinant CXCL3 protein is produced in Escherichia coli (E. coli).

Quick Overview for CXCL3 Protein (AA 32-100) (TRX tag) (ABIN7668514)

Target: CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))

Protein Type: Recombinant

Biological Activity: Inactive

Origin: Mouse

Source: Escherichia coli (E. coli)

Purity: > 90 %

Product Details

Protein Characteristics: AA 32-100

Purification tag / Conjugate: This CXCL3 protein is labelled with TRX tag.

Purpose: Recombinant Mouse CXCL3/CINC-2α/β Protein(Trx Tag)

Sequence: Ser32-Ser100

Purification: SDS-PAGE analysis of Mouse CXCL3/CINC-2α/β proteins, 2 μg/lane of Recombinant Mouse CXCL3/CINC-2α/β proteins was resolved with SDS-PAGE under reducing conditions, showing bands at 30 KD

Sterility: 0.2 μm filtered

Endotoxin Level: < 10 EU/mg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))

Alternative Name: CXCL3

Background: CXCL3/CINC-2α/β is involved in migration, invasion, proliferation and tubule formation of trophoblasts and may play a key role in the pathogenesis of preeclampsia. CXCL3/CINC-2α/β autocrine/paracrine pathways are involved in the development of prostate cancer by regulating the expression of the target genes that are related to the progression of malignancies. CXCL3/CINC-2α/β is a novel adipokine that facilitates adipogenesis in an autocrine and/or a paracrine manner throμgh induction of c/ebpb and c/ebpd. CXCL3/CINC-2α/β and its receptor CXCR2 are overexpressed in prostate cancer cells, prostate epithelial cells and prostate cancer tissues, which may play multiple roles in prostate cancer progression and metastasis.,CSF,GRO,Dcip,CXCL,SCYB,GROg,CINC-2b,CSF-1,GRO3,MGI-IM,MIP2B,MIP-2b,SCYB3,Dcip1,Gm1960,Cxcl3

Molecular Weight:

calculated_mw: 27.5 kDa

observed_mw: 30 kDa

UniProt: Q6W5C0

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagy