Clusterin Protein (CLU) (His tag)

Catalog No. ABIN7668544

This Recombinant Clusterin protein is produced in Escherichia coli (E. coli).

Quick Overview for Clusterin Protein (CLU) (His tag) (ABIN7668544)

Target: Clusterin (CLU)

Protein Type: Recombinant

Biological Activity: Inactive

Origin: Rat

Source: Escherichia coli (E. coli)

Purity: > 95 %

Product Details

Purification tag / Conjugate: This Clusterin protein is labelled with His tag.

Purpose: Recombinant Rat Clusterin/ApoJ protein (His tag)

Sequence: Glu 22-Arg 226

Purification: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: < 10 EU/mg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: Clusterin (CLU)

Alternative Name: Clusterin,ApoJ

Background: Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. In addition,Clusterin is up/ down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others.,AAG4,AP,APOJ,Aging-Associated Gene 4 Protein,Apo-J,Apolipoprotein J,CLI,CLU,Clusterin,Complement Cytolysis Inhibitor,Complement-Associated Protein SP-40,KUB1,Ku70-Binding Protein 1,NA1/NA2,TRPM-2,Testosterone-Repressed Prostate Message 2

Molecular Weight:

calculated_mw: 22.4 kDa

observed_mw: 28 kDa

UniProt: P05371

Pathways: Apoptosis, Negative Regulation of intrinsic apoptotic Signaling