Lactoferrin Protein (His tag)

Catalog No. ABIN7669199

This Recombinant Lactoferrin protein is expressed in Escherichia coli (E. coli).

Quick Overview for Lactoferrin Protein (His tag) (ABIN7669199)

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Protein Type: Recombinant

Biological Activity: Inactive

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 %

Product Details

Purification tag / Conjugate: This Lactoferrin protein is labelled with His tag.

Purpose: Recombinant Human LTF/LF protein (His tag)

Sequence: Glu 542- Gln 685

Purification: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: < 10 EU/mg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Alternative Name: LTF,LF

Background: Lactotransferrin is a member of the transferrin family that transfer iron to the cells and control the level of free iron in the blood and external secretions. Lactotransferrin is a secreted protein and contains two transferrin-like domains. Lactotransferrin can be cleaved into the following four chains: Kaliocin-1, Lactoferroxin-A, Lactoferroxin-B, and Lactoferroxin-C. Lactoferroxin A, Lactoferroxin B, and Lactoferroxin C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while Lactoferroxin B and Lactoferroxin C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. LTF has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses.,GIG12,HEL110,HLF2,Kaliocin-1,LF,LTF,Lactoferrin,Lactoferroxin-A,Lactoferroxin-B,Lactoferroxin-C,Lactotransferrin,Talalactoferrin

Molecular Weight:

calculated_mw: 15.7 kDa

observed_mw: 16 kDa

UniProt: P02788

Pathways: Transition Metal Ion Homeostasis