SERPING1 Protein (AA 1-504) (His tag)

Catalog No. ABIN7669752

Recombinant SERPING1 protein expressed in HEK-293 Cells.

Quick Overview for SERPING1 Protein (AA 1-504) (His tag) (ABIN7669752)

Target: SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))

Protein Type: Recombinant

Biological Activity: Inactive

Origin: Rat

Source: HEK-293 Cells

Purity: > 95 %

Product Details

Protein Characteristics: AA 1-504

Purification tag / Conjugate: This SERPING1 protein is labelled with His tag.

Purpose: Recombinant Rat C1Inh protein (His tag)

Sequence: Met1-Ala504

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU/mg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))

Alternative Name: C1Inh

Background: Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein,C1 Inh,C1 esterase inhibitor,C1-inhibiting factor,C1Inh,Plasma protease C1 inhibitor,Serpin G1,Serping1

Molecular Weight:

calculated_mw: 55.3 kDa

observed_mw: 65 kDa

UniProt: Q6P734

Pathways: Complement System