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CD4 Protein (CD4) (His tag)

This Recombinant CD4 protein is produced in HEK-293 Cells.
Catalog No. ABIN7794645

Quick Overview for CD4 Protein (CD4) (His tag) (ABIN7794645)

Target

See all CD4 Proteins
CD4

Protein Type

Recombinant

Origin

  • 33
  • 8
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 31
  • 8
  • 8
  • 2
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
  • Purification tag / Conjugate

    This CD4 protein is labelled with His tag.

    Purpose

    Recombinant human CD4 Protein with C-terminal 6?His tag
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
  • Target

    CD4

    Alternative Name

    CD4

    Background

    T4, IMD79, Leu-3, OKT4D, CD4mut Background: This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]

    Molecular Weight

    Predicted: 42.1 kDa after removal of the signal peptide. The apparent molecular mass of CD4-His is approximately 35-55 kDa due to glycosylation.

    UniProt

    P01730

    Pathways

    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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