Cathepsin D Protein (CTSD) (His tag)

Catalog No. ABIN7794656

Recombinant Cathepsin D protein expressed in HEK-293 Cells.

Quick Overview for Cathepsin D Protein (CTSD) (His tag) (ABIN7794656)

Target: Cathepsin D (CTSD)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Purification tag / Conjugate: This Cathepsin D protein is labelled with His tag.

Purpose: Recombinant human CTSD Protein with C-terminal 10?His tag

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Target Details

Target: Cathepsin D (CTSD)

Alternative Name: CTSD

Background: CPSD, CLN10, HEL-S-130P Background: This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]

Molecular Weight: Predicted: 44.0 kDa after removal of the signal peptide. The apparent molecular mass of CTSD-His is approximately 35-55 kDa due to glycosylation.

UniProt: P07339

Pathways: Peptide Hormone Metabolism