Activin B Protein (ACVB) (AA 293-407)

Catalog No. ABIN7827811

This Recombinant Activin B protein is expressed in HEK-293 Cells.

Quick Overview for Activin B Protein (ACVB) (AA 293-407) (ABIN7827811)

Target: Activin B (ACVB)

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by Bis-Tris PAGE

Product Details

Protein Characteristics: AA 293-407

Purpose: Human Activin B Protein

Sequence: Gly293-Ala407

Characteristics: Recombinant Human Activin B Protein is expressed from HEK293 without tag.It contains Gly293-Ala407.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 0.1 EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human Activin B, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 10.8ng/ml determined by ELISA.,Immobilized Human Activin B, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIA, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA.,Human Activin B Protein on Bis-Tris PAGE under reduced (R) condition and Non reduced (N) condition. The purity is greater than 95%.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as 0.22 μm filtered solution in 4 mM HCL.

Storage: -80 °C

Storage Comment: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Activin B (ACVB)

Alternative Name: Activin B

Background: The gene inhibin subunit beta B (INHBB), also named Activin B encodes the inhibin βB subunit, which is involved in forming protein members of the transforming growth factor-β (TGF-β) superfamily. The TGF-β superfamily is extensively involved in cell proliferation, differentiation, adhesion, movement, metabolism, communication, and death.

Molecular Weight: 12.81 kDa. Due to glycosylation, the protein migrates to 14-15 kDa under reduced (R) condition, and 24-30 kDa under Non reduced (N) condition based on Bis-Tris PAGE result.

UniProt: P09529