CDH6 Protein (AA 22-614) (His tag)

Catalog No. ABIN7829884

Recombinant CDH6 protein expressed in HEK-293 Cells.

Quick Overview for CDH6 Protein (AA 22-614) (His tag) (ABIN7829884)

Target: CDH6 (K-Cadherin (CDH6))

Protein Type: Recombinant

Origin: Cynomolgus

Source: HEK-293 Cells

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Purity: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 22-614

Purification tag / Conjugate: This CDH6 protein is labelled with His tag.

Purpose: Recombinant Cynomolgus CDH6 protein with C-terminal 10xHis tag

Specificity: CDH6(Thr22-Gly614) 10xHis tag

Characteristics: Extracellular Domain Protein

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Comment:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: CDH6 (K-Cadherin (CDH6))

Alternative Name: CDH6

Background: CAD6, KCAD
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011]

Molecular Weight: predicted molecular mass of 67.4 kDa after removal of the signal peptide.

Pathways: Cell-Cell Junction Organization