Troponin I Protein (TNNI)

Catalog No. ABIN934444

Native Troponin I protein expressed in Sheep.

Quick Overview for Troponin I Protein (TNNI) (ABIN934444)

Target: Troponin I (TNNI)

Protein Type: Native

Origin: Sheep

Source: Sheep

Purity: > 95 % pure

Product Details

Characteristics: Purified native Sheep Troponin I protein (Skeletal Muscle)
Protein Source: Skeletal Muscle

Purification: Affinity chromatography

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Concentration: 0.25-2.0 mg/mL

Buffer: Supplied in 8 M Urea, 100 mM NaCl, 50 mM Tris.HCl, 1 mM EDTA, 15 mM beta-mercaptoethanol, pH 7.7.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -25 °C or below.

Target Details

Target: Troponin I (TNNI)

Alternative Name: Troponin I

Background: Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.
Description: Skeletal Muscle.
Alternative Names: Troponin I protein, TnI protein, Skeletal-specific troponin I protein, sTnl protein, Skeletal Muscle Troponin I protein

Molecular Weight: 24 kDa