Transferrin Protein (TF)
Quick Overview for Transferrin Protein (TF) (ABIN934749)
Target
See all Transferrin (TF) ProteinsProtein Type
Origin
Source
Application
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Characteristics
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Highly purified rat transferrin protein
Protein Source: Normal serum -
Purification
- Delipidation and selective precipitation followed by dialysis
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Buffer
- 0.01 M Na3PO4, pH 7.6, with 0.21 M NaCl.
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Handling Advice
- Dilute only prior to immediate use.
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Storage
- 4 °C
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- Transferrin (TF)
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Alternative Name
- Transferrin
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Background
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Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids. In humans, it is encoded by the TF gene. Transferrin is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1 % (4 mg) of the total body iron, it is the most important iron pool, with the highest rate of turnover (25 mg/24 h). Transferrin has a molecular weight of around 80 kDa and contains 2 specific high-affinity Fe(III) binding sites.
Description: Normal serum.
Alternative Names: Serotransferrin precursor protein, PRO1400 protein, beta 1 metal binding globulin protein, Apotransferrin protein, DKFZp781D0156 protein, TF protein, Siderophilin protein, PRO2086 protein, PRO1557 protein -
Pathways
- Transition Metal Ion Homeostasis
Target
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