Tropomyosin Protein
Quick Overview for Tropomyosin Protein (ABIN934829)
Target
See all Tropomyosin (TPM1) ProteinsProtein Type
Origin
Source
Purity
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Characteristics
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Purified native Human Tropomyosin protein
Protein Source: Human cardiac tissue
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Tropomyosin 1 (Alpha) (TPM1) (AA 1-284) protein (His tag)
custom-made TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tropomyosin 1 (Alpha) (TPM1) (AA 1-284) protein (His tag)custom-made TPM1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tropomyosin 1 (Alpha) (TPM1) (AA 1-245) protein (GST tag)TPM1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 5) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Buffer
- 10 mM TRIS-HCl, pH 7.4, with 50 mM NaCl, 5 mM beta-mercaptoethanol and 5 mM EDTA.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
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Alternative Name
- Tropomyosin
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Background
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Tropomyosin is an actin-binding protein that regulates actin mechanics. It is important, among other things, for muscle contraction. Tropomyosin, along with the troponin complex, associate with actin in muscle fibers and regulate muscle contraction by regulating the binding of myosin. In resting muscle, tropomyosin overlays the myosin binding sites on actin, with a single tropomyosin molecule spanning 7 actin subunits, and is locked down in this position by troponin T (tropomyosin binding troponin) and troponin I (inhibitory troponin).
Description: Human cardiac tissue. -
Pathways
- Regulation of Actin Filament Polymerization
Target
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