Tropomyosin Protein (AA 1-284) (His tag)
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- Target See all Tropomyosin (TPM1) Proteins
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-284
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Tropomyosin protein is labelled with His tag.
- Purpose
- Human TPM1 Protein
- Sequence
- Met1-Met284
- Characteristics
- Recombinant Human TPM1 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Met284.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product TPM1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS, 150 mM NaCl ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
- Alternative Name
- TPM1 (TPM1 Products)
- Synonyms
- alpha-fTM Protein, Tm7 Protein, tpm1 Protein, MGC84844 Protein, AA986836 Protein, AI854628 Protein, TM2 Protein, Tm3 Protein, Tmpa Protein, Tpm-1 Protein, alpha-TM Protein, Alpha-tm Protein, Tma2 Protein, Tmsa Protein, TPM1 Protein, fb37a09 Protein, tm Protein, wu:fb37a09 Protein, CH1 Protein, alpha-tm Protein, alpha-tropomyosin Protein, C15orf13 Protein, CMD1Y Protein, CMH3 Protein, HTM-alpha Protein, TMSA Protein, TPMA Protein, Tm1 Protein, zgc:171719 Protein, zgc:55951 Protein, zgc:77009 Protein, tropomyosin 1 (alpha) Protein, tropomyosin Protein, tropomyosin 1 Protein, tropomyosin 1, alpha Protein, alpha-tropomyosin Protein, tropomyosin 1 L homeolog Protein, TPM1 Protein, tm7 Protein, Tpm1 Protein, tpma Protein, tpm1.L Protein, Smp_044010.2 Protein, LOC732984 Protein, tpm1 Protein
- Background
- Tropomyosin-1 (TPM1), a widely expressed actin-binding protein, is downregulated in many tumors and associated with cancer progression. TPM1 overexpression in RCC cell lines can induce tumor cell apoptosis via the p53-mediated mitochondrial pathway. Further studies are needed to fully elucidate the potential of TPM1 as a candidate for RCC targeted therapy in the future.
- Molecular Weight
- 34.26 kDa same as Tris-Bis PAGE result.
- NCBI Accession
- NP_000357
- Pathways
- Regulation of Actin Filament Polymerization
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