VWF Protein
Quick Overview for VWF Protein (ABIN934842)
Target
See all VWF ProteinsProtein Type
Origin
Source
Purity
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Characteristics
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Purified native Human VWF protein (Factor VIII Free)
Protein Source: Human serum/plasma
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Buffer
- 25 mM sodium citrate, 105 M NaCl, 105 M Glycine, pH 6.8.
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Precaution of Use
- Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -80 °C
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Storage Comment
- Aliquot and store at -80 °C or lower.
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- VWF (Von Willebrand Factor (VWF))
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Alternative Name
- VWF
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Background
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Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that is required for normal hemostatic platelet plug formation. The mature plasma protein is composed of apparently identical subunits (Mr=260,000) which are held together by disulfide bonds. The circulating vWF molecule ranges in size from dimers (Mr=520,000) to extremely large multimers (Mr>10,000,000). During normal hemostasis, the larger multimers of vWF are responsible for facilitating platelet plug formation by forming a bridge between platelet glycoprotein IB and exposed collagen in the subendothelium.
Description: Human serum/plasma.
Alternative Names: Von Willebrand Factor VIII Free Protein -
Molecular Weight
- 260 kDa
Target
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