alpha Synuclein E46K (active) Protein

Catalog No. ABIN934881

This Recombinant protein is expressed in Escherichia coli (E. coli).

Quick Overview for alpha Synuclein E46K (active) Protein (ABIN934881)

Target: alpha Synuclein E46K

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % pure

Product Details

Protein Characteristics: active

Sequence: MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKKGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA

Characteristics: Purified recombinant Human alpha Synuclein E46 K protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Application Details

Application Notes: Alpha synuclein protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, containing 0.1 M NaCl.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: alpha Synuclein E46K

Background: Alpha-synuclein E46K is a mutant form of alpha-synuclein which is changed at position 46 from glutamate(E) to lysine(K). Recent studies have shown that this mutant(E46K) of alpha-synuclein causes Parkinson and Lewy Body dementia(DLB). Alpha-synuclein E46K was overexpressed in E. coli and purified to apparent homogeneity by using conventional column chromatography techniques.
Alternative Names: Parkinson disease familial 1 protein, PD1 protein, Non-A4 component of amyloid precursor protein, alpha synuclein E46k protein, PD 1 protein, Alpha synuclein protein, alphaSYN protein, Non A beta component of AD amyloid protein, Non A4 component of amyloid precursor protein, Synuclein alpha protein, MGC110988 protein, alpha-synuclein e46k protein, MGC64356 protein, NACP protein, Non-A-beta component of alzheimers disease amyloid protein, precursor of PARK 1 protein, alpha-Synuclein protein, Non-A beta component of AD amyloid protein, MGC105443 protein, SNCA protein, MGC127560 protein, Alpha-synuclein isoform NACP140 protein, PARK4 protein, PARK1 protein, , PARK 4 protein

Molecular Weight: 14.4 kDa (140 AA)