IPP-POZ Domain (AA 1-157) Protein

Catalog No. ABIN934905

Product Details

Target: IPP-POZ Domain

Protein Type: Recombinant

Protein Characteristics: AA 1-157

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MANEDCPKAA DSPFSSDKHA QLILAQINKM RNGQHFCDVQ LQVGQESFKA HRLVLAASSP YFAALFTGGM KESSKDVVPI LGIEAGIFQI LLDFIYTGIV NIGVNNVQEL IIAADMLQLT EVVHLCCEFL KGQIDPLNCI GIFQFSEQIA CHDLLEF

Characteristics: Purified recombinant Human IPPPOZ domain protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Purity: > 95 % pure

Application Details

Application Notes: IPPPOZ protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 10 mM HEPES, pH7.4, 20 mM NaCl.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: IPP-POZ Domain

Background: Intracisternal A particle-promoted polypeptide(IPP) is a 66kDa protein (584 amino acids), which contains an N-terminal POZ protein-protein interaction domain and a C-termina kelch repeat domain consisting of six tandem arranged repeats. The POZ domain (also called BTB domain) is present near the N-terminus of a fraction of zinc finger proteins and in proteins that contain the pfam01344 motif such as kelch and pox virus proteins. The BTB/POZ domain mediates homomeric dimerization and in some instances heteromeric dimerization. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-coR and SMRT. IPP-POZ domain (1-157aa) was overexpressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: Protein phosphatase 1 regulatory subunit 1A, Actin binding protein IPP protein, Protein phosphatase inhibitor 1 protein, MIPP protein protein, Intracisternal A particle promoted polypeptide protein, Kelch like protein 27 protein, IPP-POZ domain protein, KLHL27 protein, I1 protein, IPP POZ protein, Actin-binding protein IPP protein, IPP protein, Intracisternal A particle-promoted polypeptide isoform 1 protein, Kelch-like protein 27 protein

Molecular Weight: 17.3 kDa (157 AA)