PTH Protein
Quick Overview for PTH Protein (ABIN934912)
Target
See all PTH ProteinsProtein Type
Origin
Source
Application
Purity
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Sequence
- MSVSEIQLMH NLGKHLNSME RVEWLRKKLQ DVHNFVALGA PLAPRDAGSQ RPRKKEDNVL VESHEKSLGE ADKADVNVLT KAKSQ
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Characteristics
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Purified recombinant Human Parathyroid Hormone protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.
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Application Notes
- Parathyroid hormone protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Supplied as a liquid in PBS, pH 7.4, containing 2 mM EDTA.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- PTH (Parathyroid Hormone (PTH))
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Alternative Name
- Parathyroid Hormone
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Target Type
- Hormone
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Background
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Human parathyroid hormone (hPTH) is an 84 amino acid residue peptide and one of the main regulators in maintenance of calcium homeostasis. It acts primarily on kidney and bone cells stimulating calcium resorption or calcium mobilization, respectively. The whole mechanism is still under discussion, but low-dose hPTH triggers cyclic AMP-dependent protein kinase in some populations of bone cells bearing PTH receptors, which stimulates the proliferation of osteoblasts. Human parathyroid hormone(amino acids 1-84) was overexpressed in E. coli and purified to apparent homogeneity by using conventional column chromatography techniques.
Alternative Names: Parathormone protein, Human Parathyroid Hormone protein, Parathyroid hormone protein, hPTH protein, PTH protein, PTH protein, Parathyrin protein, Parathormone protein -
Molecular Weight
- 9.55 kDa (85 AA)
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Pathways
- cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
Target
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