G-CSF Protein

Catalog No. ABIN934916

This Recombinant G-CSF protein is produced in Escherichia coli (E. coli).

Quick Overview for G-CSF Protein (ABIN934916)

Target: G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % pure

Product Details

Sequence: MTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQP

Characteristics: Purified recombinant Human GCSF protein
Expression System: E.coli
Bioactivity: The proliferative activity of rhG-CSF is tested in culture using murine bone marrow cells.
Molecular weight on SDS-PAGE will appear higher.

Application Details

Application Notes: GCSF protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied as a liquid in PBS, pH 7.4.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))

Alternative Name: GCSF

Background: Human granulocyte colony-stimulating factor (hG-CSF) is one of the hematopoietic growth factors which plays an important role in stimulating proliferation, differentiation, and functional activation of blood cells. In addition to its effect on hematopoiesis, G-CSF also enhances neutrophil functions against bacteria, fungi, and tumor cells mediated by antibody-dependent cell-mediated cytotoxicity. Recombinant hG-CSF was expressed in E. coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Alternative Names: CSF3 protein, Csfg protein, CSF beta protein, Granulocyte-colony stimulating factor Colony stimulating factor 3 (granulocyte) protein, MGC45931 protein, CSF 3 protein, , Granulocyte colony stimulating factor protein, Lenograstim protein, Filgrastim protein, Pluripoietin protein, GCSA protein, GCSF protein, Lenograstim protein, Macrophage granulocyte inducer 2 protein, G-CSF protein, G-CSF protein, MGI 2 protein, Granulocyte colony-stimulating factor protein

Molecular Weight: 18.8 kDa (175 AA)

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization