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IgG2b Protein (AA 502-636, Fasciclin Domain 4)

This Recombinant IgG2b protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN934938

Quick Overview for IgG2b Protein (AA 502-636, Fasciclin Domain 4) (ABIN934938)

Target

IgG2b

Protein Type

Recombinant

Origin

Human

Source

  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 95 % pure
  • Protein Characteristics

    Fasciclin Domain 4, AA 502-636

    Sequence

    MGTVMDVLKG DNRFSMLVAA IQSAGLTETL NREGVYTVFA PTNEAFRALP PRERSRLLGD AKELANILKY HIGDEILVSG GIGALVRLKS LQGDKLEVSL KNNVVSVNKE PVAEPDIMAT NGVVHVITNV LQPPA

    Characteristics

    Purified recombinant Human BIGH3 protein
    Expression System: E.coli
    Molecular weight on SDS-PAGE will appear higher.
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  • Application Notes

    BIGH3 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Supplied as a liquid in 20 mM Tris, pH 8.0.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    RT/-20 °C

    Storage Comment

    Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
  • Target

    IgG2b

    Alternative Name

    IGH3

    Target Type

    Antibody

    Background

    BIGH3, also known as TGFBI and betaig-h3, is an extracellular matrix protein induced by transforming growth factor(TGF)-beta 1. BIGH3 protein is involved in cell growth, cell differentiation, wound healing and cell adhesion. In addition, some missense mutations of BIGH3 were identified in families affected with human autosomal dominant corneal dystrophies. BIGH3 gene encodes for a 683 amino-acid protein containing an RGD motif and four internal repeated domains which have highly conserved sequences founded in several species (Fasciclin domain). Recombinant human BIGH3 protein was expressed in E. coli and purified by using conventional chromatography techniques.
    Alternative Names: CSD1 protein, beta induced protein, Beta ig h3 protein, CDB1 protein, TGFBI protein, BIGH -3 protein, CSD protein, AI747162 protein, LCD1 protein, Fasciclin domain 4 protein, RGD CAP protein, BIGH3 protein, RGD-CAP protein, BIGH3, EBMD protein, CSD2 protein, CSD3 protein, AI181842 protein, TGFBI transforming growth factor protein, RGD containing collagen associated protein protein, BIGH -3, Kerato epithelin protein, CDG2 protein, Beta ig-h3 protein, big h3 protein, CDGG1 protein, Beta ig protein, BIGH 3, Transforming growth factor-beta-induced protein ig-h3 protein, MGC150270 protein, Transforming growth factor beta induced protein ig h3., RGD-containing collagen-associated protein protein, Kerato-epithelin protein, BIGH 3 protein, 68kDa protein, BIGH3 protein

    Molecular Weight

    14.5 kDa (135 AA)
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