YWHAB Protein (AA 1-246)

Catalog No. ABIN934969

Recombinant YWHAB protein expressed in Escherichia coli (E. coli).

Quick Overview for YWHAB Protein (AA 1-246) (ABIN934969)

Target: YWHAB (14-3-3 alpha + beta (YWHAB))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 % pure

Product Details

Protein Characteristics: AA 1-246

Sequence: MTMDKSELVQ KAKLAEQAER YDDMAAAMKA VTEQGHELSN EERNLLSVAY KNVVGARRSS WRVISSIEQK TERNEKKQQM GKEYREKIEA ELQDICNDVL ELLDKYLIPN ATQPESKVFY LKMKGDYFRY LSEVASGDNK QTTVSNSQQA YQEAFEISKK EMQPTHPIRL GLALNFSVFY YEILNSPEKA CSLAKTAFDE AIAELDTLNE ESYKDSTLIM QLLRDNLTLW TSENQGDEGD AGEGEN

Characteristics: Purified recombinant Human 14.3.3 beta protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Application Details

Application Notes: 14.3.3 beta protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris, pH 8.0, containing 0 mM EDTA, and 50 mM NaCl.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: YWHAB (14-3-3 alpha + beta (YWHAB))

Background: The 14-3-3 family plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon,sigma, zeta, tau and eta that have been identified in mammals. The 14-3-3 beta, a subtype of the 14-3-3 proteins, was found in B Cells, brain and liver etc. This 14-3-3 beta has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Recombinant human 14-3-3 beta was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: Protein kinase C inhibitor protein 1 protein, Tyrosine 3 Monooxygenase/Tryptophan 5 Monooxygenase Activation Protein Beta Polypeptide., Brain protein 14 3 3 beta isoform protein, HS1 protein, 14-3-3 beta, 14-3-3 beta protein, beta polypeptide protein, KCIP-1 protein, GW 128 protein, Protein 1054 protein, YWHAB protein, 14.3.3 beta, HS 1 protein, 14/3/3 beta protein, beta polypeptide 14 3 3 protein beta/alpha protein, GW128 protein, 14-3-3 beta protein, KCIP 1 protein, Tyrosine 3-monocxygenase/tryptopan 5-monooxygenase activation protein protein, Tyrosine 3-monocxygenase/tryptopan 5-monooxygenase activation protein protein, KCIP1 protein, 14/3/3 beta

Molecular Weight: 28 kDa (246 AA)

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location