BID Protein (AA 1-195)

Catalog No. ABIN934976

This Recombinant BID protein is produced in Escherichia coli (E. coli).

Quick Overview for BID Protein (AA 1-195) (ABIN934976)

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % pure

Product Details

Protein Characteristics: AA 1-195

Sequence: MDCEVNNGSS LRDECITNLL VFGFLQSCSD NSFRRELDAL GHELPVLAPQ WEGYDELQTD GNRSSHSRLG RIEADSESQE DIIRNIARHL AQVGDSMDRS IPPGLVNGLA LQLRNTSRSE EDRNRDLATA LEQLLQAYPR DMEKEKTMLV LALLLAKKVA SHTPSLLRDV FHTTVNFINQ NLRTYVRSLA RNGMD

Characteristics: Purified recombinant Human BID protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Application Details

Application Notes: BID protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl, pH 8.0, containing 20 % glycerol.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Alternative Name: BID

Background: BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into the outer mitochondrial membrane. Bax is believed to induce the opening of the mitochondrial voltage-dependent anion channel. This results in the release of cytochrome c and other pro-apoptotic factors from the mitochondria leading to activation of caspases. Recombinant BID protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: p22 BID., p13 BID protein, Apoptotic death agonist BID protein, BH3 interacting domain death agonist isoform 2 Apoptotic death agonist protein, Human BID coding sequence protein, BH3 interacting domain death agonist p11 protein, MGC42355 protein, p11 BID protein, BID isoform L(2) protein, OTTHUMP00000196197 protein, BH3 interacting domain death agonist p13 protein, MGC15319 protein, HGNC:1050 protein, BID protein, BH3 interacting domain death agonist protein, BID isoform ES(1b) protein, p15 BID protein, BH3 interacting domain death agonist p15 protein, BH3 interacting domain death agonist isoform 2 protein, Desmocollin type 4 protein, FP497 protein

Molecular Weight: 21.9 kDa (195 AA)

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity