HSC70 Interacting Protein HIP Protein (AA 1-369)
Quick Overview for HSC70 Interacting Protein HIP Protein (AA 1-369) (ABIN935011)
Target
See all HSC70 Interacting Protein HIP (ST13) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-369
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Sequence
- MDPRKVNELR AFVKMCKQDP SVLHTEEMRF LREWVESMGG KVPPATQKAK SEENTKEEKP DSKKVEEDLK ADEPSSEESD LEIDKEGVIE PDTDAPQEMG DENAEITEEM MDQANDKKVA AIEALNDGEL QKAIDLFTDA IKLNPRLAIL YAKRASVFVK LQKPNAAIRD CDRAIEINPD SAQPYKWRGK AHRLLGHWEE AAHDLALACK LDYDEDASAM LKEVQPRAQK IAEHRRKYER KREEREIKER IERVKKAREE HERAQREEEA RRQSGAQYGS FPGGFPGGMP GNFPGGMPGM GGGMPGMAGM PGLNEILSDP EVLAAMQDPE VMVAFQDVAQ NPANMSKYQS NPKVMNLISK LSAKFGGQA
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Characteristics
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Purified recombinant Human Hip/ST13 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. -
Endotoxin Level
- < 1.0 EU per µg of protein (determined by LAL method)
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Suppression of Tumorigenicity 13 (ST13) (AA 1-369) protein (His tag)
custom-made ST13 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Suppression of Tumorigenicity 13 (ST13) (AA 1-371) protein (His tag)custom-made ST13 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Suppression of Tumorigenicity 13 (ST13) (AA 1-369) protein (GST tag)ST13 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Suppression of Tumorigenicity 13 (ST13) (AA 1-58) protein (GST tag)ST13 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Suppression of Tumorigenicity 13 (ST13) protein (Myc-DYKDDDDK Tag)ST13 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Hip/ST13 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0 mM DTT, 0.1 M NaCl, and 10 % glycerol.
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Preservative
- Dithiothreitol (DTT)
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Precaution of Use
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))
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Alternative Name
- Hip/ST13
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Background
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Hip (Hsc70-interacting protein), also known as ST13, is a co-chaperone to the major heat shock proteins, Hsp70 and Hsp90, and appears in early receptor complexes. Through mutual binding to both Hsp70 and Hsp90, Hip functions as an adaptor that can integrate Hsp70 and Hsp90 interactions. Also, Hip has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. Recombinant human Hip was expressed in E. coli and purified by using conventional chromatography.
Alternative Names: Hip/ST 13, Hip/ST13, Hsc70-interacting protein protein, HOP protein, Hip/ST 13 protein, FAM10A1 protein, ST13 protein, SNC6 protein, Hip/ST-13 protein, Hip/ST-13, Hsc70-interacting protein -
Molecular Weight
- 41.3 kDa (369 AA)
Target
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