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Latexin Protein (LXN) (AA 1-222)

Recombinant Latexin protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN935023

Quick Overview for Latexin Protein (LXN) (AA 1-222) (ABIN935023)

Target

See all Latexin (LXN) Proteins
Latexin (LXN)

Protein Type

Recombinant

Origin

  • 8
  • 5
  • 3
Human

Source

  • 9
  • 3
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 95 % pure
  • Protein Characteristics

    AA 1-222

    Sequence

    MEIPPTNYPA SRAALVAQNY INYQQGTPHR VFEVQKVKQA SMEDIPGRGH KYRLKFAVEE IIQKQVKVNC TAEVLYPSTG QETAPEVNFT FEGETGKNPD EEDNTFYQRL KSMKEPLEAQ NIPDNFGNVS PEMTLVLHLA WVACGYIIWQ NSTEDTWYKM VKIQTVKQVQ RNDDFIELDY TILLHNIASQ EIIPWQMQVL WHPQYGTKVK HNSRLPKEVQ LE

    Characteristics

    Purified recombinant Human Latexin protein
    Expression System: E.coli
    Molecular weight on SDS-PAGE will appear higher.

    Endotoxin Level

    < 1.0 EU per µg of protein (determined by LAL method)
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  • Application Notes

    Latexin protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Supplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, containing 50 mM NaCl, and 10 % glycerol.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    RT/-20 °C

    Storage Comment

    Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
  • Target

    Latexin (LXN)

    Alternative Name

    Latexin

    Background

    Latexin, a carboxypeptidase A inhibitor, is highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low expression occurs in other tissues including brain. Latexin has no detectable sequence similarity with plant and parasite inhibitors, but it is related to a human putative tumor suppressor protein, TIG1. It is down-regulated in the presenilin-1-deficient mouse brain, thus putatively playing a role in Alzheimer's disease. Recombinant human Latexin protein was expressed in E. coli and purified by using conventional chromatography.
    Alternative Names: Endogenous carboxypeptidase inhibitor protein, ECI protein, TCI protein, Latexin protein, Latexin protein protein, Tissue carboxypeptidase inhibitor., LXN protein, MUM protein

    Molecular Weight

    25.7 kDa (222 AA)
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