CBR1 Protein (AA 1-277)
Quick Overview for CBR1 Protein (AA 1-277) (ABIN935034)
Target
See all CBR1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-277
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Sequence
- MSSGIHVALV TGGNKGIGLA IVRDLCRLFS GDVVLTARDV TRGQAAVQQL QAEGLSPRFH QLDIDDLQSI RALRDFLRKE YGGLDVLVNN AGIAFKVADP TPFHIQAEVT MKTNFFGTRD VCTELLPLIK PQGRVVNVSS IMSVRALKSC SPELQQKFRS ETITEEELVG LMNKFVEDTK KGVHQKEGWP SSAYGVTKIG VTVLSRIHAR KLSEQRKGDK ILLNACCPGW VRTDMAGPKA TKSPEEGAET PVYLALLPPD AEGPHGQFVS EKRVEQW
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Characteristics
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Purified recombinant Human CBR1 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.
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Carbonyl Reductase 1 (CBR1) (AA 1-277) protein (GST tag)
CBR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Carbonyl Reductase 1 (CBR1) (AA 2-277), (full length) protein (GST tag)CBR1 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % SDS, ELISA
Carbonyl Reductase 1 (CBR1) (AA 45-320), (partial) protein (His tag)CBR1 Origin: Human Host: Yeast Recombinant > 90 % SDS
Carbonyl Reductase 1 (CBR1) protein (Myc-DYKDDDDK Tag)CBR1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- CBR1 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.5, containing 10 % glycerol.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- CBR1 (Carbonyl Reductase 1 (CBR1))
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Alternative Name
- CBR1
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Background
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CBR1 (Carbonyl reductase 1) is one of several monomeric NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. CBR1 is widely distributed in human tissues. CBR1 metabolizes many toxic environmental quinones and pharmacologically relevant substrates such as the anticancer doxorubicin. CBR1 can also convert prostaglandin E2 to prostaglandin F2-alpha. Recombinant human CBR1 protein was expressed in E. coli and purified by using conventional chromatography.
Alternative Names: Carbonyl reductase 1 15 hydroxyprostaglandin dehydrogenase [NADP+] protein, CBR1 protein, CBR 1, Carbonyl reductase [NADPH] 1.CBR 1 protein, CBR protein, hCBR1 protein, SDR21C1 protein, Prostaglandin E(2) 9 reductase., NADPH dependent carbonyl reductase 1 protein, CBR-1, CRN protein, Carbonyl reductase 1 protein, CBR1, Prostaglandin 9 ketoreductase protein, CBR 1 protein, CBR-1 protein -
Molecular Weight
- 30 kDa (277 AA)
Target
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