HINT1 Protein (AA 1-126)

Catalog No. ABIN935039

This Recombinant HINT1 protein is produced in Escherichia coli (E. coli).

Quick Overview for HINT1 Protein (AA 1-126) (ABIN935039)

Target: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 % pure

Product Details

Protein Characteristics: AA 1-126

Sequence: MADEIAKAQV ARPGGDTIFG KIIRKEIPAK IIFEDDRCLA FHDISPQAPT HFLVIPKKHI SQISVAEDDD ESLLGHLMIV GKKCAADLGL NKGYRMVVNE GSDGGQSVYH VHLHVLGGRQ MHWPPG

Characteristics: Purified recombinant Human HINT1 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Application Details

Application Notes: HINT1 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 10 % glycerol.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Alternative Name: HINT1

Background: HINT1, also known as Histidine triad nucleotide-binding protein 1, is a member of a superfamily named for a near C-terminal HXHXHXX motif (H:Histidine, X:a hydrophobic amino acid) positioned at the alpha-phosphate of nucleotide substrates. This protein hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2. Although it was originally thought to be a protein kinase C inhibitor and act as a haplod-insufficient tumor suppressor including spontaneous tumor formation in Hint+/- and Hint-/- , its actual physiologic function is not known. Recombinant human HINT1 protein was expressed in E. coli and purified by using conventional chromatography.
Alternative Names: PKCI1 protein, HINT 1 protein, Histidine triad nucleotide binding protein 1 protein, HINT1, Histidine triad nucleotide-binding protein 1 Adenosine 5' monophosphoramidase protein, Histidine triad nucleotide-binding protein 1 protein, PKCI 1 protein, HINT 1, HINT protein, HINT-1 protein, PKCI-1 protein, Protein kinase C interacting protein 1., PRKCNH1 protein, HINT 1 protein, HINT-1, Protein kinase C inhibitor 1 protein

Molecular Weight: 13.8 kDa (126 AA)