VSNL1 Protein (AA 1-191)

Catalog No. ABIN935057

This Recombinant VSNL1 protein is produced in Escherichia coli (E. coli).

Quick Overview for VSNL1 Protein (AA 1-191) (ABIN935057)

Target: VSNL1 (Visinin-Like 1 (VSNL1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % pure

Product Details

Protein Characteristics: AA 1-191

Sequence: MGKQNSKLAP EVMEDLVKST EFNEHELKQW YKGFLKDCPS GRLNLEEFQQ LYVKFFPYGD ASKFAQHAFR TFDKNGDGTI DFREFICALS ITSRGSFEQK LNWAFNMYDL DGDGKITRVE MLEIIEAIYK MVGTVIMMKM NEDGLTPEQR VDKIFSKMDK NKDDQITLDE FKEAAKSDPS IVLLLQCDIQ K

Characteristics: Purified recombinant Human Visininlike protein1 protein
Expression System: E.coli

Endotoxin Level: < 1.0 EU per µg of protein (determined by LAL method)

Application Details

Application Notes: Visininlike 1 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0 mM DTT, and 10 % glycerol.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: VSNL1 (Visinin-Like 1 (VSNL1))

Alternative Name: Visininlike protein1

Background: Visinin-like protein-1, also known as VILIP-1, belongs to a family of neuronal calcium sensor proteins. VILIP-1 is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Also, it is expressed in pancreatic beta-cells. VILIP-1 elevation enhances insulin secretion in cAMP-associated manner. Down-regulation of VILIP-1 decreased cAMP accumulation but increased insulin gene transcription. Recombinant human Visinin-like protein-1 was expressed in E. coli and purified by using conventional chromatography.
Alternative Names: Neurocalcin alpha protein, Visinin.Visinin like 1 protein, HLP3 protein, NVL1 protein, Visininlike 1, HLP 3 protein, Visinin like protein 1.VISL 1., NVL 1 protein, VILIP-1 protein, VILIP protein, VILIP protein, HPCAL 3 protein, Visininlike -1 protein, Visininlike -1, Visininlike 1, VSNL1 protein, Visininlike 1 protein, Hippocalcin like protein 3 protein, HUVISL1 protein, VLP-1 protein, HPCAL3 protein

Molecular Weight: 22.1 kDa (191 AA)