alpha Actinin Protein
Quick Overview for alpha Actinin Protein (ABIN935139)
Target
See all alpha Actinin (ACTN) ProteinsProtein Type
Origin
Source
Purity
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Characteristics
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Purified native Chicken alpha Actinin protein
Protein Source: Chicken gizzard
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- 1 mg/mL
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Buffer
- Supplied in lyophilized form with 10 mM Tris/HCl buffer pH 8.0, 0.2 mM CaCl2, 0.2 mM ATP, 1 mM DTT, 0.5 % (w/v) SDS.
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Preservative
- Dithiothreitol (DTT)
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Precaution of Use
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2-8 °C in lyophilized form. Following reconstitution aliquot and store at -20 °C for long term storage.
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- alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
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Alternative Name
- alpha Actinin
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Background
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Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.
Description: Chicken gizzard.
Alternative Names: alpha Actinin 1 protein, ACTN1 protein, FLJ40884 protein -
Molecular Weight
- 95 kDa
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Pathways
- Cell-Cell Junction Organization, Negative Regulation of Transporter Activity
Target
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