Bacillus anthracis Protein
Origin: Bacillus anthracis
Host: Escherichia coli (E. coli)
Recombinant
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- Target See all Bacillus anthracis products
- Bacillus anthracis
- Protein Type
- Recombinant
- Origin
- Bacillus anthracis
- Source
- Escherichia coli (E. coli)
- Characteristics
- Purified recombinant Bacillus Anthracis (Anthrax) protein (Lethal Antigen)
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from 50 mM NaCl, 0 mM HEPES, pH 7.5.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C
- Storage Comment
- Store at 4 °C.
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- Target
- Bacillus anthracis
- Abstract
- Bacillus anthracis Products
- Target Type
- Bacteria
- Background
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One of the three protein components of Anthrax toxin, protective antigen (PA) is the central moiety that mediates the entry of lethal factor and edema factor into the target cell. PA binds to the cell surface via a type I membrane protein with a von Willebrand factor A domain called anthrax toxin receptor. After proteolytic activation to a 63 kDa fragment, PA self-associates to form a heptameric cation-selective, voltage-gated membrane channel.
Alternative Names: Bacillus Anthracis Protein, Recombinant B Anthracis , Anthrax Protein, Bacillus Anthracis Lethal Antigen Recombinant Protein - Molecular Weight
- 83 kDa
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