ApoE2 Protein

Catalog No. ABIN935204

This Recombinant ApoE2 protein is produced in Escherichia coli (E. coli).

Quick Overview for ApoE2 Protein (ABIN935204)

Target: ApoE2 (apoe2) (Apolipoprotein E2 (apoe2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 90 % pure

Product Details

Sequence: MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSEQVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET RARLSKELQA AQARLGADME DVCGRLVQYR GEVQAMLGQS TEELRVRLAS HLRKLRKRLL RDADDLQKCL AVYQAGAREG AERGLSAIRE RLGPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRDRL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKVQAAVGT SAAPVPSDNH

Characteristics: Purified recombinant Human ApoE2 protein
Expression System: E.coli

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from 20 mM Na3PO4, pH 7.8, with 0.0 mM DTT.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: ApoE2 (apoe2) (Apolipoprotein E2 (apoe2))

Alternative Name: ApoE2

Background: ApoE exists in three major isoforms, E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. Defects in ApoE are a cause of hyperlipoproteinemia type III due to increased plasma cholesterol and triglycerides levels which are the consequence of impaired clearance of chylomicron and VLDL remnants.
Alternative Names: ApoE-2 protein, ApoE-2, Apo-E2 protein, ApoE 2 protein, ApoE 2, ApoE2, Apo E2 protein, Apolipoprotein E2 protein

Molecular Weight: 34.3 kDa