ACVA Protein
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- Target See all ACVA Proteins
- ACVA (Activin A (ACVA))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS
- Characteristics
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Purified recombinant Human Activin A protein
Expression System: E.coli
Bioactivity: The ED50 as determined by its ability to inhibit the proliferation of Mouse MPC-11 cells is ? 2.0 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg. - Purity
- > 97 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product ACVA Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- ACVA (Activin A (ACVA))
- Alternative Name
- Activin A (ACVA Products)
- Synonyms
- inhibin beta A subunit Protein, Inhba Protein
- Background
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Activin A is a TGF beta family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF beta antagonist, Follistatin.
Alternative Names: Inhibin beta-A protein, Activin beta-A protein - Molecular Weight
- 26 kDa
- Pathways
- Hormone Transport, Peptide Hormone Metabolism
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