ADIPOQ Protein
Quick Overview for ADIPOQ Protein (ABIN935219)
Target
See all ADIPOQ ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- RGHHHHHHHH ETTTQGPGVL LPLPKGACTG WMAGIPGHPG HNGAPGRDGR DGTPGEKGEK GDPGLIGPKG DIGETGVPGA EGPRGFPGIQ GRKGEPGEGA YVYRSAFSVG LETYVTIPNM PIRFTKIFYN QQNHYDGSTG KFYCNIPGLY YFSYHITVYM KDVKVSLFKK DKAVLFTYDQ YQEKNVDQAS GSVLLHLEVG DQVWLQVYGD GDHNGLYADN VNDSTFTGFL LYHDTN
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Characteristics
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Purified recombinant Human Adiponectin protein
Expression System: Hi-5 cells
Bioactivity: Determined by a cytotoxic assay using M1 cells. The ED50 for this effect is 3.0-6.0 µg/mL. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Comment
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Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 1.0 mg/mL.
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Buffer
- Lyophilized from 20 mM tris, pH 8.5, with 250 mM L-arginine.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- ADIPOQ (Adiponectin (ADIPOQ))
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Alternative Name
- Adiponectin
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Background
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Adiponectin is an adipose-derived secreted protein containing 226 amino acid residues. It is relatively abundant in humans and rodents, accounting for about 0.01 % of total plasma protein. The circulating levels of adiponectin are decreased under conditions of obesity, insulin resistance, and type II diabetes. Disruption of adiponectin in mice causes insulin resistance and neointimal formation. Conversely, administration of recombinant adiponectin suppresses hepatic glucose production, and reverses insulin resistance associated with both lipoatrophy and obesity.
Alternative Names: Acrp-30 protein, Apm-1 protein, GBP-28 protein
Target
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