Defensin beta 3 Protein (DEFB3)
Quick Overview for Defensin beta 3 Protein (DEFB3) (ABIN935229)
Target
See all Defensin beta 3 (DEFB3) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
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Characteristics
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Purified recombinant Human BD3 protein
Expression System: E.coli
Bioactivity: Exhibits antimicrobial activity against gram-positive bacteria S. aureus and gram-negative P. aeruginosa and E.coli. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Defensin beta 3 (DEFB3) (Active) protein
DEFB3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Defensin beta 3 (DEFB3) (AA 23-63) protein (His tag)DEFB3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Defensin beta 3 (DEFB3) (AA 23-67) protein (His tag)DEFB3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in 10 mM Acetic Acid to a concentration of 0.1 - 1.0 mg/mL.
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Buffer
- Supplied lyophilized with no additives.
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Preservative
- Without preservative
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Defensin beta 3 (DEFB3)
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Alternative Name
- BD3
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Background
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Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells.
Alternative Names: BD-3 protein, BD 3, BD 3 protein, BD3, BD-3 protein, beta-defensin-3 protein, BD 3 protein, BD-3 -
Molecular Weight
- 3.9 kDa
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Pathways
- Production of Molecular Mediator of Immune Response
Target
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