BMP6 Protein
Quick Overview for BMP6 Protein (ABIN935246)
Target
See all BMP6 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- VSSASDYNSS ELKTACRKHE LYVSFQDLGW QDWIIAPKGY AANYCDGECS FPLNAHMNAT NHAIVQTLVH LMNPEYVPKP CCAPTKLNAI SVLYFDDNSN VILKKYRNMV VRACGCH
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Characteristics
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Purified recombinant Human BMP6 protein
Expression System: HEK cells
Bioactivity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 this effect is 0.03-0.06 µg/mL. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Bone Morphogenetic Protein 6 (BMP6) (AA 21-510) protein (His tag)
BMP6 Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Bone Morphogenetic Protein 6 (BMP6) (AA 21-513) protein (His tag)BMP6 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Bone Morphogenetic Protein 6 (BMP6) (AA 382-513), (partial) protein (His tag)BMP6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Bone Morphogenetic Protein 6 (BMP6) protein (Myc-DYKDDDDK Tag)BMP6 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Bone Morphogenetic Protein 6 (BMP6) proteinBMP6 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- Lyophilized from 10 mM Tris, pH 9.0.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- BMP6 (Bone Morphogenetic Protein 6 (BMP6))
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Alternative Name
- BMP6
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Background
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TGF beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. Increasing evidence indicates that BMP-Smad signaling has a tumor suppressing activity and that BMPs can inhibit tumor growth. BMP-6 is abnormally expressed in breast cancer cell lines, however, its function in promoting breast cancer development is unknown.
Alternative Names: BMP 6 protein, VGR protein, BMP6, Bone Morphogenetic protein 6 protein, BMP-6, BMP-6 protein, BMP-6 protein, BMP 6 -
Molecular Weight
- 26.2 kDa
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Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
Target
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