BMP7 Protein

Catalog No. ABIN935247

This Recombinant BMP7 protein is expressed in CHO Cells.

Quick Overview for BMP7 Protein (ABIN935247)

Target: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: CHO Cells

Purity: > 98 % pure

Product Details

Sequence: MANVAENSSS DQRQACKKHE LYVSFRDLGW QDWIIAPEGY AAYYCEGECA FPLNSYMNAT NHAIVQTLVH FINPETVPKP CCAPTQLNAI SVLYFDDSSN VILKKYRNMV VRACGCH

Characteristics: Purified recombinant Human BMP7 protein
Expression System: CHO cells
Bioactivity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.02-0.04 µg/mL.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Alternative Name: BMP7

Background: BMP-7, also known as osteogenic protein-1 or OP-1, is a potent bone inducing agent, which in the presence of appropriate osteoconductive carrier (e.g. collagen sponge or synthetic hydroxyapatite) can be used in the treatment of bone defects. A bone-graft substitute, called OP-1TM implant, made of recombinant human BMP-7 associated with bovine bone-derived collagen, has recently been approved by the FDA as a device for treating critical-size bone fractures.
Alternative Names: BMP 7 protein, BMP7, Bone Morphogenetic protein 7 protein, BMP-7, BMP-7 protein, OP-1 protein, BMP 7, BMP-7 protein

Molecular Weight: 28.8 kDa

Pathways: Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance