Defensin beta 4 Protein (DEFB4) (AA 33-47)

Catalog No. ABIN935250

This Recombinant Defensin beta 4 protein is expressed in Escherichia coli (E. coli).

Quick Overview for Defensin beta 4 Protein (DEFB4) (AA 33-47) (ABIN935250)

Target: Defensin beta 4 (DEFB4)

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Protein Characteristics: AA 33-47

Sequence: EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP

Characteristics: Purified recombinant Human BD4 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-100.0 ng/mL.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: Defensin beta 4 (DEFB4)

Alternative Name: BD4

Background: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence. beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta-defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. BD-4 is expressed in testis, stomach, uterus, neutrophils, thyroid, lung and kidney.
Alternative Names: BEFB4 protein, BD 4 protein, beta-defensin 104 protein, BD 4 protein, BD-4, BD-4 protein, BD 4, BD4, BD-4 protein

Molecular Weight: 6.0 kDa