Endoglin Protein (ENG)
Quick Overview for Endoglin Protein (ENG) (ABIN935304)
Target
See all Endoglin (ENG) ProteinsProtein Type
Origin
Source
Purity
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Characteristics
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Purified recombinant Human CD105 protein
Expression System: Sf-9 insect cells -
Endotoxin Level
- < 0.1 ng per µg of sCD105
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder. Reconsitute by adding a carrier protein (e.g. 0.1 % HSA or BSA) which allows for long term storage.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C/-80 °C
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Storage Comment
- Store at -70 °C until reconstitution. Following reconstitution product should be aliquoted and frozen at -20 °C.
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- Endoglin (ENG)
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Alternative Name
- CD105
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Background
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Endoglin (CD105) is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Endoglin has been found to be part of the TGF-beta1 receptor complex. It thus may be involved in the binding of TGF-beta1, TGF-beta3, activin-A, BMP-2, and BMP-7.
Alternative Names: CD105, Endoglin protein, CD 105, CD 105 protein, CD-105, CD-105 protein -
Molecular Weight
- approx. 90 kDa
Target
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