IL-3 Protein
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- Target See all IL-3 Proteins
- IL-3 (Interleukin 3 (IL-3))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF
- Characteristics
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Purified recombinant Human IL3 protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ? 0.1 ng/mL, corresponding to a specific activity of ? 1 x 10^7 units/mg. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product IL-3 Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
- Buffer
- Supplied lyophilized with no additives.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
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- Target
- IL-3 (Interleukin 3 (IL-3))
- Alternative Name
- IL3 (IL-3 Products)
- Background
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IL3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL3 may have additional immunoregulatory roles. Many of the IL3 activities depend upon co-stimulation with other cytokines.
Alternative Names: IL-3 protein, Multi-CSF protein, Interleukin 3 protein, HCGF protein, IL-3, IL 3, IL-3 protein, IL 3 protein, Mast cell growth factor protein, MCGF protein, P-cell stimulation factor protein, IL3 - Molecular Weight
- 15 kDa
- Pathways
- JAK-STAT Signaling, Regulation of Carbohydrate Metabolic Process, Autophagy
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