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IL-3 Protein

IL-3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Catalog No. ABIN935490
  • Target See all IL-3 Proteins
    IL-3 (Interleukin 3 (IL-3))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 23
    • 14
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 29
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF
    Characteristics
    Purified recombinant Human IL3 protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ? 0.1 ng/mL, corresponding to a specific activity of ? 1 x 10^7 units/mg.
    Purity
    > 98 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
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    Discover our top product IL-3 Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
    Buffer
    Supplied lyophilized with no additives.
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    RT/-20 °C
  • Target
    IL-3 (Interleukin 3 (IL-3))
    Alternative Name
    IL3 (IL-3 Products)
    Background
    IL3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL3 may have additional immunoregulatory roles. Many of the IL3 activities depend upon co-stimulation with other cytokines.
    Alternative Names: IL-3 protein, Multi-CSF protein, Interleukin 3 protein, HCGF protein, IL-3, IL 3, IL-3 protein, IL 3 protein, Mast cell growth factor protein, MCGF protein, P-cell stimulation factor protein, IL3
    Molecular Weight
    15 kDa
    Pathways
    JAK-STAT Signaling, Regulation of Carbohydrate Metabolic Process, Autophagy
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