ILGFBP1 (full length) (Active) Protein

Catalog No. ABIN935502

This Recombinant ILGFBP1 protein is expressed in Escherichia coli (E. coli).

Quick Overview for ILGFBP1 (full length) (Active) Protein (ABIN935502)

Target: ILGFBP1

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Protein Characteristics: full length

Characteristics: Purified recombinant Human ILGFBP1 protein
Expression System: E.coli
Bioactivity: Inhibition of IGF-I stimulated proliferation of NUC-1 cells: IC50 ~ 100 ng/mL Inhibition of serum-induced stimulation of DNA synthesis in chick embryo fibroblast primary cultures: IC50 (1 % serum) ~300 ng/mL.

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 20 mM CH3COOH at the stock concentration of not less than 0.1 mg/mL.

Buffer: Supplied as a lyophilized powder.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Target Details

Target: ILGFBP1

Background: IGFBP1 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alternative Names: ILGFBP-1, hIGFBP-1 protein, PP12 protein, ILGFBP1, ILGFBP 1, ILGFBP-1 protein, ILGFBP-1 protein, AFBP protein, ILGFBP 1 protein, IGF-BP25 protein, IGF-Binding Protein 1 protein, IBP-1 protein, IGFBP-1 protein, Insulin Like Growth Factor Binding Protein 1 protein

Molecular Weight: 25.3 kDa