IL-20 Protein
Quick Overview for IL-20 Protein (ABIN935560)
Target
See all IL-20 (IL20) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE
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Characteristics
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Purified recombinant Human IL20 protein
Expression System: E.coli
Bioactivity: Determined by its ability to activate STAT following receptor ligand interaction. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Interleukin 20 (IL20) (AA 25-176) protein (His tag)
IL20 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 20 (IL20) (AA 25-176) protein (Fc Tag)IL20 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 20 (IL20) (AA 25-176) protein (His tag)IL20 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 20 (IL20) (AA 25-176) (Active) protein (His tag)IL20 Origin: Human Host: Escherichia coli (E. coli) > 90 % AcA, CC Active
Interleukin 20 (IL20) (AA 25-176) protein (Fc Tag)IL20 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 20 (IL20) (AA 1-176) protein (GST tag)IL20 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- IL-20 (IL20) (Interleukin 20 (IL20))
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Alternative Name
- IL20
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Background
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IL20 is a member of the IL10 family of regulatory cytokines which includes IL10, IL19, IL20, IL22, IL24 and IL26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL20 signals through a receptor system composed of type I IL20R-a and type II IL20R-beta. Over-expression of IL20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease.
Alternative Names: Interleukin 20 protein, IL-20 protein, IL-20, IL 20 protein, IL 20, IL20, IL-20 protein -
Molecular Weight
- 35.2 kDa
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Pathways
- Protein targeting to Nucleus
Target
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