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Interleukin 17a Protein

This Recombinant Interleukin 17a protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN935580

Quick Overview for Interleukin 17a Protein (ABIN935580)

Target

See all Interleukin 17a (IL17A) Proteins
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 22
  • 12
  • 3
  • 2
  • 2
  • 2
  • 1
Mouse

Source

  • 16
  • 11
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 98 % pure
  • Sequence

    MAAIIPQSSA CPNTEAKDFL QNVKVNLKVF NSLGAKVSSR RPSDYLNRST SPWTLHRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPESCPF TFRVEKMLVG VGCTCVASIV RQAA

    Characteristics

    Purified recombinant Mouse IL17 A protein
    Expression System: E.coli
    Bioactivity: Measured by its ability to induce IL-6 production by NIH 3T3 cells.

    Endotoxin Level

    < 0.1 ng per µg (1 EU/µg).
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  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Supplied as a lyophilized powder.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    RT/-20 °C
  • Target

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    Alternative Name

    IL17A

    Background

    The originally described IL17 protein, now known as IL17A, is a disulfide linked homodimer, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL17A through IL17F, are secreted as homodimers. IL17A exhibits cross-species bioactivity between human and Mouse cells.
    Alternative Names: ILA 17 protein, Interleukin 17A protein, IL-17A protein, IL-17 protein, CTLA-8 protein, ILA-17 protein, ILA-17, ILA 17, IL17A

    Molecular Weight

    30 kDa
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