Interleukin 17a Protein
Quick Overview for Interleukin 17a Protein (ABIN935580)
Target
See all Interleukin 17a (IL17A) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MAAIIPQSSA CPNTEAKDFL QNVKVNLKVF NSLGAKVSSR RPSDYLNRST SPWTLHRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPESCPF TFRVEKMLVG VGCTCVASIV RQAA
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Characteristics
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Purified recombinant Mouse IL17 A protein
Expression System: E.coli
Bioactivity: Measured by its ability to induce IL-6 production by NIH 3T3 cells. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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Alternative Name
- IL17A
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Background
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The originally described IL17 protein, now known as IL17A, is a disulfide linked homodimer, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL17A through IL17F, are secreted as homodimers. IL17A exhibits cross-species bioactivity between human and Mouse cells.
Alternative Names: ILA 17 protein, Interleukin 17A protein, IL-17A protein, IL-17 protein, CTLA-8 protein, ILA-17 protein, ILA-17, ILA 17, IL17A -
Molecular Weight
- 30 kDa
Target
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