IL-33 Protein
Quick Overview for IL-33 Protein (ABIN935587)
Target
See all IL-33 (IL33) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSKI
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Characteristics
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Purified recombinant Mouse IL33 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse D10S cells is ? 0.5 ng/mL, corresponding to a specific activity of ? 2 x 10^6units/mg. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Interleukin 33 (IL33) (AA 1-266) protein (His tag)
custom-made IL33 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interleukin 33 (IL33) (AA 1-270) protein (His tag)custom-made IL33 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interleukin 33 (IL33) (AA 109-270) (Active) protein (His tag)IL33 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 33 (IL33) (AA 109-264) protein (His tag)IL33 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interleukin 33 (IL33) (AA 109-270) protein (His tag)IL33 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 33 (IL33) protein (His tag)IL33 Origin: Rhesus Monkey Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Interleukin 33 (IL33) (AA 171-269) protein (GST tag)IL33 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 33 (IL33) (AA 1-270) protein (GST tag)IL33 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- IL-33 (IL33) (Interleukin 33 (IL33))
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Alternative Name
- IL33
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Background
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IL33 is a proinflammatory protein that shares structural and functional characteristics with the IL1 cytokine family. It binds and signals through the IL1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL33 induces production of TH2 cell related cytokines, including IL4, IL5 and IL13, and exerts multiple inflammation related bioactivities.
Alternative Names: NF-HEV protein, IL-33 protein, IL 33 protein, IL-33, IL33, IL-33 protein, IL 33, Interleukin 33 protein -
Molecular Weight
- 17.5 kDa
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Pathways
- Production of Molecular Mediator of Immune Response
Target
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