MSTN Protein
Quick Overview for MSTN Protein (ABIN935645)
Target
See all MSTN ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- DFGLDCDEHS TESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGECEFV FLQKYPHTHL VHQANPRGSA GPCCTPTKMS PINMLYFNGK EQIIYGKIPA MVVDRCGCS
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Characteristics
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Purified recombinant Human Myostatin protein
Expression System: E.coli
Contaminants: Supplied lyophilized with no additives.
Bioactivity: Determined by its ability to inhibit the proliferation of MPC-11 cells. The expected ED50 for this effect is 17.0-25.0 ng/mL. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Myostatin (MSTN) (Active) protein
MSTN Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Myostatin (MSTN) (AA 24-375) protein (Fc Tag)MSTN Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Myostatin (MSTN) (AA 267-375) protein (His-IF2DI Tag)MSTN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Myostatin (MSTN) (AA 1-375) protein (GST tag)MSTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Myostatin (MSTN) proteinMSTN Origin: Human Host: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with water to 0.1 - 1.0 mg/mL . Due to the solubility reasons the protein should be kept at low pH.
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Buffer
- Lyophilized with no additives.
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Preservative
- Without preservative
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- MSTN (Myostatin (MSTN))
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Alternative Name
- Myostatin
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Background
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Myostatin is a TGF beta family member that acts as an inhibitor of skeletal muscle growth. This muscle-specific cytokine interacts with Activin type I and type II receptors, and suppresses myoblast proliferation by arresting cell-cycle in the G1 phase. Suppression of myostatin activity facilitates muscle formation and may be useful in reducing and/or preventing adiposity and type-2 diabetes. Myostatin activity can be blocked by the Activin-binding protein Follistatin, and by the propeptide of Myostatin.
Alternative Names: GDF-8 protein -
Molecular Weight
- 25 kDa
Target
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