CCL4 Protein
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- Target See all CCL4 Proteins
- CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- APIGSDPPTS CCFSYTSRKI HRNFVMDYYE TSSLCSQPAV VFLTKKGRQI CADPSEPWVN EYVNDLELN
- Characteristics
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Purified recombinant Human MIP1 beta protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human monocytes using a concentration range of 0.01-1.0 µg/mL. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product CCL4 Protein
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Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) (Active) protein
CCL4 Origin: Human Host: Escherichia coli (E. coli) Recombinant CMA Active
Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) protein (GST tag)CCL4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) (Active) protein (Biotin)CCL4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 26-92) protein (His tag)Crystallography grade CCL4 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) protein (His tag)Crystallography grade CCL4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) protein (His tag)Crystallography grade CCL4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
- Alternative Name
- MIP1 beta (CCL4 Products)
- Synonyms
- ACT2 Protein, AT744.1 Protein, G-26 Protein, HC21 Protein, LAG-1 Protein, LAG1 Protein, MIP-1-beta Protein, MIP1B Protein, MIP1B1 Protein, SCYA2 Protein, SCYA4 Protein, CCL4 Protein, K203 Protein, Mip1-b Protein, Scya4 Protein, MIP-1beta Protein, MIP-1BETA Protein, MIP1b Protein, SCY4A Protein, Act-2 Protein, MIP-1B Protein, Mip1b Protein, ACT-2 Protein, AT744.2 Protein, CCL4L Protein, SCYA4L Protein, SCYA4L1 Protein, SCYA4L2 Protein, C-C motif chemokine ligand 4 Protein, chemokine (C-C motif) ligand 4 Protein, chemokine (C-C motif) ligand 4-like 1 Protein, C-C motif chemokine ligand 4 like 1 Protein, CCL4 Protein, Ccl4 Protein, CCL4L1 Protein
- Background
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Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells.
Alternative Names: Macrophage Inflammatory Protein-1beta protein, CCL4 protein, MIP beta 1 protein, MIP-1 beta protein, ACT-2 protein, MIP1 beta, MIP beta-1, MIP beta 1, MIP beta-1 protein - Molecular Weight
- 7.8 kDa
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