MDC69 (Active) Protein

Catalog No. ABIN935666

This Recombinant MDC69 protein is produced in Escherichia coli (E. coli).

Quick Overview for MDC69 (Active) Protein (ABIN935666)

Target: MDC69

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Sequence: GPYGANMEDS VCCRDYVRYR LPLRVVKHFY WTSDSCPRPG VVLLTFRDKE ICADPRVPWV KMILNKLSQ

Characteristics: Purified recombinant Human MDC69 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human T cells using a concentration range of 10.0-100.0 ng/mL.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: MDC69

Background: MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity.
Alternative Names: ABCD-1 protein, Macrophage-Derived Chemokine protein, MDC 69, MDC-69 protein, MDC 69 protein, STCP-1 protein, MDC-69, MDC69, MDC-69 protein, CCL22 protein

Molecular Weight: 8.0 kDa