CLCF1 Protein
Quick Overview for CLCF1 Protein (ABIN935688)
Target
See all CLCF1 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MLNRTGDPGP GPSIQKTYDL TRYLEHQLRS LAGTYLNYLG PPFNEPDFNP PRLGAETLPR ATVDLEVWRS LNDKLRLTQN YEAYSHLLCY LRGLNRQAAT AELRRSLAHF CTSLQGLLGS IAGVMAALGY PLPQPLPGTE PTWTPGPAHS DFLQKMDDFW LLKELQTWLW RSAKDFNRLK KKMQPPAAAV TLHLGAHGF
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Characteristics
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Purified recombinant Human NNT1 protein
Expression System: E.coli
Bioactivity: NT-1/BCSF-3 weakly supports chick E8 DRG neurite outgrowth at a concentration of 1.0 ng/mL. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 29-225) protein (GST tag)
CLCF1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 28-225) protein (His tag)CLCF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Cardiotrophin-Like Cytokine Factor 1 (CLCF1) proteinCLCF1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CLCF1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
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Alternative Name
- NNT1
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Background
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NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member beta (LIFR-beta) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM.
Alternative Names: NNT-1 protein, NNT-1 protein, Novel Neurtrophin-1/B-Cell Stimulating Factor-3 protein, Cardiotrophin-like cytokine protein, NNT 1, NNT 1 protein, NNT1, NNT-1 -
Molecular Weight
- 22.4 kDa
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Target
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